His inverted-ziggurat design was opened October 21, 1959 and has been recognized as a masterpiece of architecture ever since. Located in the Upper East side at East 89th and 5th Avenue the building's modern shape stands out amongst its more traditional neighbors so you can't miss it! One of the key features is the sweeping spiral ramp that rises toward the domed skylight. It's a classic that no doubt you've seen, even if you've never visited the museum, as it has been featured in many movies and television shows. Known for being the Museum of Non-Objective Painting the Guggenheim has exhibited works from Mondrian, Chagall, Delaunay, and Picasso to name a few.